The Titans will host the 49ers in a Thursday night battle with playoff implications for both teams.
Coming off a 19-13 loss to the Steelers, the Titans (9-5) will be looking to stay atop the AFC South standings. A win against San Francisco would keep Tennessee above Indianapolis (8-6), which has won eight of its past 11 games after starting the season 0-3.
In the loss to the Steelers, Titans quarterback Ryan Tannehill threw for just 153 yards and turned the ball over twice. The Tennessee offense fared much better on the ground with the team rushing for more than 200 yards, including 108 yards from running back D’Onta Foreman. However, with leading wide receiver A.J. Brown back on the field, Tannehill should be able to find more success through the air.
MORE: Is A.J. Brown playing on Thursday night?
The 49ers (8-6), meanwhile, are hoping to extend their winning streak to three games and hold onto an NFC wild-card spot. Kyle Juszczyk, Deebo Samuel and Jeff Wilson Jr. each scored rushing touchdowns in a win over Atlanta on Sunday, but it could be difficult to find running lanes against Tennessee. The Titans rank second in the league in rushing yards allowed per game (86.9) behind only the Ravens (86.2).
Sporting News is tracking live scoring updates and highlights from 49ers vs. Titans on “Thursday Night Football.” Follow along below for complete results from the NFL Week 16 game.
MORE: Watch 49ers vs. Titans live with fuboTV (7-day free trial)
49ers vs. Titans score
| Q1 | Q2 | Q3 | Q4 | F | |
| 49ers | — | — | — | — | — |
| Titans | — | — | — | — | — |
49ers vs. Titans live updates, highlights from Thursday Night Football
Kickoff is scheduled for 8:20 p.m. ET. Live updates will begin at that time.
49ers vs. Titans start time
- Date: Thursday, Dec. 23
- Time: 8:20 p.m. ET
The 49ers vs. Titans game will kick off at 8:20 p.m. ET in Week 16. Pregame coverage of the contest will begin at 7:30 p.m. ET on NFL Network. NFL Network will also air “TNF First Look” on game day starting at 3 p.m. ET.
Streamers will be able to watch the game via fuboTV, which comes with a seven-day free trial.
Viewers in Canada can watch the game on DAZN.
How to watch Thursday Night Football
The NFL Network will have the exclusive broadcast for “Thursday Night Football,” as it is no longer simulcasting the game with Fox. The program was only available on NFL Network early in the season but has been a simulcast over the past two-plus months. Joe Buck will be on play-by-play duties, and Troy Aikman will provide color commentary.
Most United States cable providers carry the NFL Network. It is also available via satellite provider DirecTV (channels 212 and 1212) and IPTV providers Verizon FiOS (channels 88 and 588) and Google Fiber (channel 2019).
49ers schedule 2021
| Week | Date | Opponent | Kickoff time | TV |
| 1 | Sept. 12 | at Lions | 1 p.m. ET | Fox |
| 2 | Sept. 19 | at Eagles | 1 p.m. ET | Fox |
| 3 | Sept. 26 | vs. Packers | 8:20 p.m. ET | NBC |
| 4 | Oct. 3 | vs. Seahawks | 4:05 p.m. ET | Fox |
| 5 | Oct. 10 | at Cardinals | 4:25 p.m. ET | Fox |
| 6 | BYE | — | — | — |
| 7 | Oct. 24 | vs. Colts | 8:20 p.m. ET | NBC |
| 8 | Oct. 31 | at Bears | 1 p.m. ET | Fox |
| 9 | Nov. 7 | vs. Cardinals | 4:25 p.m. ET | Fox |
| 10 | Nov. 15 | vs. Rams | 8:15 p.m. ET | ESPN |
| 11 | Nov. 21 | at Jaguars | 1 p.m. ET | Fox |
| 12 | Nov. 28 | vs. Vikings | 4:25 p.m. ET | Fox |
| 13 | Dec. 5 | at Seahawks | 8:20 p.m. ET | NBC |
| 14 | Dec. 12 | at Bengals | 1 p.m. ET | CBS |
| 15 | Dec. 19 | vs. Falcons | 4:05 p.m. ET | CBS |
| 16 | Dec. 23 | at Titans | 8:20 p.m. ET | NFL Network |
| 17 | Jan. 2 | vs. Texans | 4:05 p.m. ET | CBS |
| 18 | Jan. 9 | at Rams | 4:25 p.m. ET | Fox |
Titans schedule 2021
| Week | Date | Opponent | Kickoff time (ET) | TV |
| 1 | Sept. 12 | vs. Cardinals | 1 p.m. | CBS |
| 2 | Sept. 19 | at Seahawks | 4:25 p.m. | CBS |
| 3 | Sept. 26 | vs. Colts | 1 p.m. | CBS |
| 4 | Oct. 3 | at Jets | 1 p.m. | CBS |
| 5 | Oct. 10 | at Jaguars | 1 p.m. | CBS |
| 6 | Oct. 18 | vs. Bills | 8:15 p.m. | ESPN |
| 7 | Oct. 24 | vs. Chiefs | 1 p.m. | CBS |
| 8 | Oct. 31 | at Colts | 1 p.m. | CBS |
| 9 | Nov. 7 | at Rams | 7:20 p.m. | NBC |
| 10 | Nov. 14 | vs. Saints | 1 p.m. | CBS |
| 11 | Nov. 21 | vs. Texans | 1 p.m. | CBS |
| 12 | Nov. 28 | at Patriots | 1 p.m. | CBS |
| 13 | BYE | — | — | — |
| 14 | Dec. 12 | vs. Jaguars | 1 p.m. | CBS |
| 15 | Dec. 19 | at Steelers | 1 p.m. | CBS |
| 16 | Dec. 23 | vs. 49ers | 7:20 p.m. | NFL Network |
| 17 | Jan. 2 | vs. Dolphins | 1 p.m. | CBS |
| 18 | Jan. 9 | at Texans | 1 p.m. | CBS |