Oklahoma vs. Oklahoma State odds, prediction, betting trends for Week 12 matchup

By | November 19, 2022

Oklahoma hosts in-state rival and No. 24 Oklahoma State Saturday night at OU Memorial Stadium (7:30 p.m. ET on ABC) in the 2022 rendition of the Bedlam Series. Oklahoma State looks to stay in the Big 12 championship hunt while Oklahoma is attempting to end its current two-game skid.

After a 6-1 start to the season, Oklahoma State dropped two straight games to Kansas State and Kansas but did enough to get back in the win column last week against Iowa State. The Cowboys are still hanging around in the Big 12 standings, needing some help from Kansas State to potentially make it back to the championship game.

Meanwhile, 5-5 Oklahoma comes into Week 12 off an unimpressive 23-20 road loss to West Virginia. In the loss, the Sooners outgained West Virginia 424-406 and averaged 1.6 more yards per play but scored just eight second-half points to West Virginia’s 17 points. Oklahoma’s in danger of missing a bowl game for the first time since 1998.


Can Oklahoma State notch its second-straight win in the Bedlam Series or can the Sooners build some positivity with the regular season coming to a close? Here’s everything to know about betting on the Week 12 matchup between the Sooners and Cowboys: 

Oklahoma vs. Oklahoma State odds 

Odds courtesy of BetMGM

  • Spread: Oklahoma -7.5
  • Over/Under: 66
  • Moneyline: Oklahoma -300; Oklahoma State +240

After opening up as 5.5-point home favorites in the preseason, Oklahoma currently sits as 7.5-point home chalk. The line hasn’t budged much with some uncertainty surrounding Oklahoma State’s QB situation. The total has dropped to 66 after reopening at 67.5.

Three trends to know 

— Oklahoma State has had trouble winning in Norman, sporting a 1-8 record in its past nine trips to OU. Back in 2014, the Cowboys upset then-No. 20 Oklahoma, 38-35.

— The Cowboys catch the Sooners at an opportune time, as Oklahoma enters Week 12 with a 1-6 ATS mark over its past seven games.

— According to BetQL, Mike Gundy is 20-7 during his tenure at Oklahoma State in road games where the total is between 63.5 and 70.

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Three things to watch  

—The conclusion of the Bedlam Series: With Oklahoma slated to join the SEC in 2025, the Bedlam Series will soon come to an end. While the series has been one-sided (90-19-7 in favor of OU), the annual in-state showdown has brought its iconic moments and been a staple in college football’s late-season rivalry slate. Saturday marks one of the final times the two schools will meet on the gridiron, so you know emotions will be high. 

—How effective will Spencer Sanders be?: Sanders has been dealing with a shoulder injury throughout the season, missing the Kansas game and coming off the bench last week. After freshman Gunnar Gundy tossed an ill-advised interception in the third quarter last week, Sanders played the rest of the game and led the Cowboys to a come-from-behind win. Sanders already said he’ll be a go this week, and while he did enough to lead the Cowboys to a victory, much of it had to do with the ineffectiveness of Iowa State’s offense. Oklahoma State is going to have to score more than 20 points if they want to hang around with the Sooners.

—Will Oklahoma become bowl-eligible?: It’s wild to even type that out for a team that entered 2022 with College Football Playoff aspirations, but Oklahoma needs one more victory to become bowl eligible. While it’s likely the Sooners win one of their final two games to notch a bowl bid, year one of the Brent Venables era has been beyond underwhelming. Just getting to a bowl isn’t going to cut it for a program that prides itself on competing for National Championships on a yearly basis, and we’ll see if the program is able to bounce back next season.

Oklahoma vs. Oklahoma State Prediction 

If Spencer Sanders was near 100 percent, the current spread would not be over a touchdown. Oklahoma would still be a short home favorite, as a 3.5-point handicap would be more in line with the game’s projection. We expect Oklahoma to notch its sixth win to get to bowl eligibility, but we’ll side with the Cowboys getting 7.5 against the spread, thinking their defense does enough to limit Oklahoma’s offensive output.

Prediction: Oklahoma 30, Oklahoma State 27. Oklahoma State (+7.5) covers the spread with the game going UNDER the total (66).