Is DeAndre Hopkins playing Monday night? Fantasy injury update for Cardinals-49ers Week 11 Monday Night Football

By | November 20, 2022

DeAndre Hopkins has been one of the NFL’s busiest receivers since returning from his season-opening six-game suspension, but a hamstring injury threatens to put him on the sidelines again ahead of Monday night’s game against the 49ers. Nervous fantasy football owners will be checking for the latest updates before finalizing their Week 11 start ’em, sit ’em decisions, and we’ll be here to help.

We’ll continue to update this article with news on Hopkins until the official active/inactive report comes out on Monday around 6:45 p.m. ET.

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Is DeAndre Hopkins playing Monday night Week 11? 

Hopkins (hamstring) managed two limited practice sessions to close out the week, but his “questionable” tag is still a legitimate worry with the Cardinals not playing until Monday night. Originally, coach Kliff Kingsbury implied that Hopkins was just taking it easy for “maintenance” purposes, so we’ll have to hope he was telling the truth. 

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At this point, it’s worth waiting for Hopkins. However, if you do, you need to have someone like Jauan Jennings, Robbie Anderson, or Greg Dortch available as an emergency fill-in. None of those guys figures to do much, but it’s better to have the chance at some points as opposed to a guaranteed zero. You could also try TE Trey McBride or RB Keaontay Ingram in your flex spot.

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If Hopkins is active, he’ll remain a must-start. This is the first time we’ll see him, Rondale Moore, and Marquise Brown all in action together, but with Zach Ertz (knee) out for the season, there should still be enough targets to go around in Arizona’s uptempo offense even if Colt McCoy starts in place of Kyler Murray (hamstring) again. 

If Hopkins is out, it should mean even more targets for Moore and Brown, who are already decent starting options. It could also mean more targets for McBride, who would have some sleeper appeal.